A Non-Small Cell Lung Cancer Begins In The Flat Cells That Line The Airways And Can Spread Rapidly

Non-Small Cell Lung Cancer (NSCLC) is the most common type of lung cancer, accounting for approximately 85% of all cases. It is a highly aggressive and often asymptomatic disease, which contributes to late-stage diagnoses and poor prognosis. However, with advancements in medical technology and research, early detection and screening strategies have become vital in improving patient outcomes.

Identifying individuals at high risk for Non-Small Cell Lung Cancer is crucial for effective screening. The primary risk factor is tobacco smoking, with a dose-response relationship between smoking exposure and lung cancer development. Other risk factors include exposure to environmental carcinogens, family history, and certain genetic mutations. Various risk assessment models, such as the National Lung Screening Trial (NLST) criteria, have been developed to select individuals eligible for screening. These models consider age, smoking history, and other factors to identify high-risk individuals who would benefit most from screening.

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